I completed my Bachelor of Science (BSc) degree in Molecular Genetics with Extramural Year at King’s College London, with my placement year taking place at the University of Oxford. Here, I worked on the development of a bacteriophage-based neuroprotective vaccine for Parkinson’s disease (PD) as well as investigating alterations in mitochondrial morphology and function in the event of a downregulation of a specific nuclear protein (REST) in a gene-edited in vitro model of PD. My BSc final year dissertation involved investigating the effects of having a particular mutation in a component of the sonic hedgehog signalling pathway (GLI2) on monogenic diabetes development. I completed my BSc degree with an overall first class honours in 2020.
I attended Imperial College London for my Master of Research (MRes) degree where I was involved in two 6-month projects. During my first project, I investigated the role of macrophages in acute myeloid leukaemia (AML) cell migration, establishing the involvement of a chemokine-based communication between macrophages and AML cells. My second project involved studying the regulation of the Rtc RNA repair system in E. coli cells. I was awarded my MRes degree with a distinction classification.
I have always been passionate about disease research, which has been reflected in my laboratory experience thus far. I developed a specific interest for studying haematological malignancies during the final year of my BSc degree, and have been pursuing research in this area since.
I aim to use a multidisciplinary approach for aiding the development of better and more targeted therapies in the clinic. For this, I exploit the in vitro and in vivo models of fusion protein-driven myeloid malignancies in our lab, and aim to identify the interactors and regulators of such oncogenic proteins using transcriptomic, proteomic and epigenomic approaches, complementing these techniques with functional studies.