EARLY STAGE
RESEARCHERS

Early researcher

Miriam Sánchez Sáez

Background

I studied Biochemistry and Molecular Biology at the Rovira i Virgili University in Tarragona, Spain. During my undergraduate studies, I was able to spend a year at the University of Geneva, Switzerland. During this stay, I was able to enter the world of research by doing my undergraduate internship in structural biology.

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Then I returned to Spain to pursue a Master's degree in Molecular Biology and Biomedicine at the University of Cantabria and the University of the Basque Country, where I was able to focus more on the field of research. Furthermore, I did my master’s thesis the paediatric oncology group within the Biocruces Bizkaia health research center.

In January 2024 I have joined Dr. Hind Medyouf's group in the Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Germany. Here, I will be carrying out my PhD studies

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Research

During my bachelor thesis, I focused on expressing and purifying the extracellular region of leptin using various molecular biology techniques, as well as gaining training in other fields such as cryo-electron microscopy.

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Subsequently, during my master's thesis, I changed my field of study and began to study the proteome of acute lymphoblastic leukemia in pediatric patients, as well as other inflammatory diseases, such as hemophagocytic syndrome (HLH), in order to find possible diagnosis and monitorization biomarkers. Due to this internship and an additional one-year stay in this group, I was able to familiarize myself with various haematological cancers and gain more interest in this diseases.

As a PhD student in Dr.Medyouf’s lab, I will be focused on understanding the cellular crosstalk between hematopoietic stem/progenitor cells (HSPCs) and their environment in the context of myelodysplastic syndromes (MDS) to uncover niche dependencies that can be used for disease interception.  

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